| 别名 | PRKDC;HYRC;HYRC1;DNA-dependent protein kinase catalytic subunit;DNA-PK catalytic subunit;DNA-PKcs;DNPK1;p460 |
| 基因名称 | PRKDC |
| 蛋白名称 | DNA-dependent protein kinase catalytic subunit |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P78527 |
| 特异性 | DNA-PKcs (Phospho Ser2056) Antibody detects endogenous levels of DNA-PKCS protein only when phosphorylated at S2056.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):YSsQD |
| 稀释度 | WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 450kDa |
| 预测分子量 | 466kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010], |
| 细胞定位 | Nucleus . Nucleus, nucleolus . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Nucleus, nucleolus . |