| 别名 | AICL CLECSF2 IFNRG1;AICL;CLECSF2;IFNRG1 |
| 基因名称 | CLEC2B |
| 蛋白名称 | C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1) |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q92478 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 16kDa |
| 预测分子量 | 16kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011] |
| 细胞定位 | SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:23929856, ECO:0000269|PubMed:29980609}; Single-pass type II membrane protein {ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:23929856}. Note=Resting NK cells contain intracellular stores of CLEC2B associated with the Golgi complex. {ECO:0000269|PubMed:23929856}. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:23929856, ECO:0000269|PubMed:29980609}; Single-pass type II membrane protein {ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:23929856}. Note=Resting NK cells contain intracellular stores of CLEC2B associated with the Golgi complex. {ECO:0000269|PubMed:23929856}. |
周一至周日 8:00-18:00
