| 别名 | ACACA;ACAC;ACC1;ACCA;Acetyl-CoA carboxylase 1;ACC1;ACC-alpha;ACACB,Acetyl CoA carboxylase 2,ACC beta,ACC2,ACCB,AcetylCoA carboxylase 2,ACCbeta,ACCβ,ACC β,;ACACA |
| 基因名称 | ACACB |
| 蛋白名称 | ACC,Acetyl-CoA carboxylase 2;ACC-beta;Acetyl-CoA carboxylase 1;ACC1; |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q13085;O00763 |
| Mouse Gene ID | 107476 |
| Mouse Swissprot No. | Q5SWU9 |
| Rat Gene ID | 60581 |
| Rat Swissprot No. | P11497 |
| 特异性 | Acetyl-CoA Carboxylase (Phospho Ser79) Monoclonal Antibody detects endogenous levels of ACC protein only when phosphorylated at S79.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):SSmSG |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:1000-1:15000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 266kDa |
| 预测分子量 | 266kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Mitochondrion |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Mitochondrion |
周一至周日 8:00-18:00
