| 基因名称 | SORT1 |
| 蛋白名称 | Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q99523 |
| Mouse Swissprot No. | Q6PHU5 |
| Rat Swissprot No. | O54861 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:500-1:2000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 100kDa |
| 预测分子量 | 92kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015], |
| 细胞定位 | Golgi apparatus, Golgi stack membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Nucleus membrane ; Single-pass type I membrane protein . Cell membrane; Single-pass type I membrane protein; Extracellular side. Lysosome membrane ; Single-pass type I membrane protein . Localized to membranes of the endoplasmic reticulum, endosomes, Golgi stack, lysosomes and nucleus. A small fraction of the protein is also localized to the plasma membrane. May also be found in SLC2A4/GLUT4 storage vesicles (GSVs) in adipocytes. Localization to the plasma membrane in adipocytes may be enhanced by insulin. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Golgi apparatus, Golgi stack membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Nucleus membrane ; Single-pass type I membrane protein . Cell membrane; Single-pass type I membrane protein; Extracellular side. Lysosome membrane ; Single-pass type I membrane protein . Localized to membranes of the endoplasmic reticulum, endosomes, Golgi stack, lysosomes and nucleus. A small fraction of the protein is also localized to the plasma membrane. May also be found in SLC2A4/GLUT4 storage vesicles (GSVs) in adipocytes. Localization to the plasma membrane in adipocytes may be enhanced by insulin. |
周一至周日 8:00-18:00
