| 别名 | NDUFS1;NADH-ubiquinone oxidoreductase 75 kDa subunit;mitochondrial;Complex I-75kD;CI-75kD |
| 基因名称 | NDUFS1 |
| 蛋白名称 | NADH-ubiquinone oxidoreductase 75 kDa subunit mitochondrial |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P28331 |
| Mouse Gene ID | 227197 |
| Mouse Swissprot No. | Q91VD9 |
| Rat Gene ID | 301458 |
| Rat Swissprot No. | Q66HF1 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 77kDa |
| 预测分子量 | 80kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011], |
| 细胞定位 | Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 细胞定位 | Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side . |
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