| 别名 | PIG19 |
| 基因名称 | LDHA |
| 蛋白名称 | L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (Cell proliferation-inducing gene 19 protein) (LDH muscle subunit) (LDH-M) (Renal carcinoma antigen NY-REN-59) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3939 |
| Human Swissprot No. | P00338 |
| Human Swissprot Link | https://www.uniprot.org/uniprotkb/P00338/entry |
| Mouse Swissprot No. | P06151 |
| Mouse Swissprot Link | http://www.uniprot.org/uniprot/P06151 |
| Rat Swissprot No. | P04642 |
| Rat Swissprot Link | http://www.uniprot.org/uniprot/O54941P04642 |
| 稀释度 | IHC-P 1:200-1000, WB 1:500-2000, IF-P/IF-F/IF-ICC 1:200-1000, ELISA 1:5000-20000 |
| 参考分子量 | 36kDa |
| 预测分子量 | 36kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | Monoclonal, rabbit, IgG, Kappa |
| 背景介绍 | The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008], |
| 信号通路 | Glycolysis / Gluconeogenesis;Cysteine and methionine metabolism;Pyruvate metabolism;Propanoate metabolism; |
| 功能 | catalytic activity:(S)-lactate + NAD(+) = pyruvate + NADH.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,disease:Defects in LDHA are a cause of exertional myoglobinuria.,online information:Lactate dehydrogenase entry,pathway:Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.,similarity:Belongs to the LDH/MDH superfamily.,similarity:Belongs to the LDH/MDH superfamily. LDH family.,subunit:Homotetramer., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
周一至周日 8:00-18:00
