| 别名 | Connective tissue growth factor (CCN family member 2;Hypertrophic chondrocyte-specific protein 24;Insulin-like growth factor-binding protein 8;IBP-8;IGF-binding protein 8;IGFBP-8);CCN2;HCS24;IGFBP8 |
| 基因名称 | CTGF |
| 蛋白名称 | Connective tissue growth factor (CCN family member 2) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1490 |
| Human Swissprot No. | P29279 |
| Human Swissprot Link | http://www.uniprot.org/uniprotkb/P29279/entry |
| Mouse Gene ID | 14219 |
| Mouse Swissprot No. | P29268 |
| Mouse Swissprot Link | http://www.uniprot.org/uniprot/P29268 |
| Rat Swissprot No. | Q9R1E9 |
| Rat Swissprot Link | http://www.uniprot.org/uniprot/O54941Q9R1E9 |
| 稀释度 | WB 1:500-2000,ELISA 1:5000-20000,IP 1:50-200 |
| 参考分子量 | 38kDa |
| 预测分子量 | 38kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | Monoclonal, rabbit, IgG, Kappa |
| 背景介绍 | The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009], |
| 功能 | function:Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.,similarity:Belongs to the CCN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 TSP type-1 domain.,similarity:Contains 1 VWFC domain.,subunit:Monomer., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
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