| 别名 | Cyclin-dependent kinase inhibitor 1 ;CDK-interacting protein 1;Melanoma differentiation-associated protein 6;MDA-6;p21;CAP20;CDKN1;CIP1;MDA6;PIC1;SDI1;WAF1; |
| 基因名称 | CDKN1A |
| 蛋白名称 | p21 |
| 推荐应用 | |
| 反应物种 | Human,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1026 |
| Human Swissprot No. | P38936 |
| Human Swissprot Link | https://www.uniprot.org/uniprotkb/P38936/entry |
| Mouse Gene ID | 12575 |
| Mouse Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12575 |
| Mouse Swissprot No. | P39689 |
| Mouse Swissprot Link | https://www.uniprot.org/uniprotkb/P39689/entry |
| 稀释度 | IHC-P 1:100-1:200,WB 1:1000-1:5000,IF-P/IF-F/IF-ICC 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200 |
| 参考分子量 | 18kDa |
| 预测分子量 | 18kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | Monoclonal, rabbit, IgG, Kappa |
| 功能 | function:May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.,induction:By p53, mezerein (antileukemic compound) and interferon beta.,PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in all adult human tissues, with 5-fold lower levels observed in the brain., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
周一至周日 8:00-18:00
