| 别名 | NDUFS3;NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial;Complex I-30kD;CI-30kD;NADH-ubiquinone oxidoreductase 30 kDa subunit |
| 基因名称 | NDUFS3 |
| 蛋白名称 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 mitochondrial |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4722 |
| Human Swissprot No. | O75489 |
| Human Swissprot Link | http://www.uniprot.org/uniprotkb/O75489/entry |
| Mouse Gene ID | 68349 |
| Mouse Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=68349 |
| Mouse Swissprot No. | Q9DCT2 |
| Mouse Swissprot Link | http://www.uniprot.org/uniprot/Q9DCT2 |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:500-1:2000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 30kDa |
| 预测分子量 | 30kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | Monoclonal, rabbit, IgG, Kappa |
| 背景介绍 | This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009], |
| 信号通路 | Oxidative phosphorylation;Alzheimer's disease;Parkinson's disease;Huntington's disease; |
| 功能 | catalytic activity:NADH + acceptor = NAD(+) + reduced acceptor.,catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol.,function:Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I 30 kDa subunit family.,subunit:Mammalian complex I is composed of 45 different subunits., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
周一至周日 8:00-18:00
