| 别名 | FTO;KIAA1752;Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein |
| 基因名称 | FTO |
| 蛋白名称 | Alpha-ketoglutarate-dependent dioxygenase FTO |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79068 |
| Human Swissprot No. | Q9C0B1 |
| Human Swissprot Link | http://www.uniprot.org/uniprotkb/Q9C0B1/entry |
| Mouse Gene ID | 26383 |
| Mouse Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26383 |
| Mouse Swissprot No. | Q8BGW1 |
| Mouse Swissprot Link | http://www.uniprot.org/uniprot/Q8BGW1 |
| Rat Gene ID | 291905 |
| Rat Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=291905 |
| Rat Swissprot No. | Q2A121 |
| Rat Swissprot Link | http://www.uniprot.org/uniprot/Q2A121 |
| 稀释度 | IHC-P 1:3000-1:20000, WB 1:1000-1:5000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 58kDa |
| 预测分子量 | 58kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | Monoclonal, rabbit, IgG, Kappa |
| 背景介绍 | This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011], |
| 功能 | function:The precise function of this protein remains to be determined.,polymorphism:At least one intronic variation within the gene predisposes to childhood and adult obesity.,similarity:Belongs to the fto family.,tissue specificity:Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
周一至周日 8:00-18:00
