| 基因名称 | OCLN |
| 蛋白名称 | Occludin;OCN |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100506658 |
| Human Swissprot No. | Q16625 |
| Human Swissprot Link | https://www.uniprot.org/uniprotkb/Q16625/entry |
| Mouse Swissprot No. | Q61146 |
| Mouse Swissprot Link | http://www.uniprot.org/uniprot/Q61146 |
| Rat Swissprot No. | Q6P6T5 |
| Rat Swissprot Link | http://www.uniprot.org/uniprot/O54941Q6P6T5 |
| 稀释度 | IHC-P 1:200-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200 |
| 参考分子量 | 65kDa |
| 预测分子量 | 59kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | Monoclonal, rabbit, IgG, Kappa |
| 背景介绍 | This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011], |
| 信号通路 | Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;Pathogenic Escherichia coli infection; |
| 功能 | protein complex assembly, cellular amino acid derivative metabolic process, sulfur metabolic process, nucleoside metabolic process, ribonucleoside metabolic process, purine nucleoside metabolic process, macromolecular complex subunit organization, purine ribonucleoside metabolic process, S-adenosylhomocysteine metabolic process, S-adenosylmethionine metabolic process, macromolecular complex assembly, protein complex biogenesis, |
| 纯化 | Protein A |
| Clonality | Monoclonal |
周一至周日 8:00-18:00
