| 别名 | High mobility group protein B1 (High mobility group protein 1) (HMG-1);HMG1 |
| 基因名称 | HMGB1 |
| 蛋白名称 | High mobility group protein B1 (High mobility group protein 1) (HMG-1) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3146 |
| Human Swissprot No. | P09429 |
| Human Swissprot Link | https://www.uniprot.org/uniprotkb/P09429/entry |
| Mouse Gene ID | 100862258 |
| Mouse Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100862258 |
| Mouse Swissprot No. | P63158 |
| Mouse Swissprot Link | https://www.uniprot.org/uniprotkb/P63158/entry |
| Rat Gene ID | 25459 |
| Rat Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25459 |
| Rat Swissprot No. | P63159 |
| Rat Swissprot Link | https://www.uniprot.org/uniprotkb/P63159/entry |
| 稀释度 | IHC-P 1:2000-1:10000, WB 1:5000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 25kDa |
| 预测分子量 | 25kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | Monoclonal, rabbit, IgG, Kappa |
| 背景介绍 | high mobility group box 1(HMGB1) Homo sapiens This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015], |
| 功能 | function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains., |
| 纯化 | Protein A |
| Clonality | Monoclonal |