| 别名 | YAP1;YAP65;Yorkie homolog;65 kDa Yes-associated protein;YAP65 |
| 基因名称 | YAP1 |
| 蛋白名称 | Yorkie homolog |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10413 |
| Human Swissprot No. | P46937 |
| Human Swissprot Link | http://www.uniprot.org/uniprotkb/P46937/entry |
| Mouse Gene ID | 22601 |
| Mouse Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22601 |
| Mouse Swissprot No. | P46938 |
| Mouse Swissprot Link | http://www.uniprot.org/uniprot/P46938 |
| Rat Gene ID | 363014 |
| Rat Gene Link | http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=363014 |
| Rat Swissprot No. | Q2EJA0 |
| Rat Swissprot Link | http://www.uniprot.org/uniprot/Q2EJA0 |
| 稀释度 | IHC-P 1:100-1:500, WB 1:500-1:2000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000 |
| 参考分子量 | 65-75kDa |
| 预测分子量 | 55kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | Monoclonal, rabbit, IgG, Kappa |
| 背景介绍 | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013], |
| 功能 | PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 WW domain.,subunit:Binds to the SH3 domain of the YES kinase. Binds to WBP1 and WBP2. Binds, in vitro, through the WW1 domain, to neural isoforms of ENAH that contain the PPSY motif., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
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